His practice covers the full scope of the patent process, from preparing, filing, and prosecuting applications before the U.S. Patent and Trademark Office to handling appeals and oral arguments before the Patent Trial and Appeal Board. He conducts post-grant proceedings, including re-examinations and reissues of granted U.S. patents, and performs strategic analyses of third-party patent assets to assess patent strength, validity, and freedom to operate.

Greg also advises clients on patent portfolio strategy, conducts worldwide patent and scientific literature searches, and provides technical counsel on pure and applied organic chemistry in support of litigation. His work spans an extensive range of technical fields beyond the chemical arts, including biotechnology, genetically modified plants, mechanical engineering, polymer science, medical devices, food science, fuel cells, semiconductors, business methods, finance, and telecommunications.

His scientific contributions include the discovery of the first general method for direct formylation of kinetically-generated ketone enolates, published in Organic Letters, and the introduction of 2,2,2-trifluoroethyl formate — known as Zayia's Reagent — into the repertoire of synthetic organic chemists. Greg is also the editor of Ricci on Glissando: The Shortcut to Violin Technique, published by Indiana University Press.